Positive ANA? What could I have?
Emma E Asked: Positive ANA? What could I have?
I ran my ANA twice, (one several months after the other, neither of which I was sick during), and both times it came up positive.1 to 160 speckled
I have cold hands and feet and mylimbs fall asleep very easily, and i have cataplexy-like symptoms.But they don't change color at all.
They ran a lupus panel, negative.
I don't have trouble walking and moving, although I always hurt everywhere
I crack my joints a lot, I go to a chiropractor, I feel it helps my circulation
I always have a headache, and sometimes it gets much worse. But I've never had a migraine.
I went to the neurologist and they ran an eeg, nothing found.
My bloods are fine, I'm not anemic or have diabetes or anything….Nothing but the positive ANA
I see a rheumatologist again soon, hope to find results….but in the meantime I'd love some possibilities…..if anyone knows….so please help?
what could I have? What are the symptoms of that? suggestions?
Mononucleosis is one type of infection that has been associated with the development of antinuclear antibodies. Some blood pressure lowering drugs and certain anti-seizure medications may trigger antinuclear antibody formation as well.
having a positive ANA does not necessarily mean you have a disease
The ANA test is a very flawed test. Many of the healthy population will test positive and have nothing wrong.
The test is measured in titers, anything under 1:40 is considered negative on paper. So the results go 1:40, 1:80, 1:160, 1:320, 1:640, 1:1280 and continues to double. My rheumatologist said that an ANA under 1:640 would be considered negative and non suggestive of an autoimmune disease.
One study studied 485 healthy volunteer blood donors and found that 20% of the women and 7% of the men had a positive ANA result. Of women over 40 years of age, 31% were ANA-positive.
Another study found an ANA titer of at least 1:640 in 15% of healthy women younger than 40 years and 24% of women age 40 or older.
In another study of healthy adults (age 20 to 60 years), found that 31.7% had a positive ANA result at a 1:40 dilution, 13.3% at a 1:80 dilution, 5% at a 1:160 dilution, and 3.3% at a 1:320 dilution.
Another study looked at 1,010 ANA results in a hospital. Fifteen percent of all patients and 30% of patients older than 65 years had a positive ANA titer of 1:40 or greater, but the positive predictive value for rheumatic disease was low. The false-positive rate for any rheumatic disease was 72% in patients 65 years old or younger, and 90% in patients older than 65 years. Even ANAs that were positive at a titer of 1:320 or greater were more likely to be falsely positive (55%) than indicative of any rheumatic disease (45%).
So studies have found, 20% of woman have a positive ANA but nothing wrong. 5% of healthy people have a positive ANA at your level. And 72% of all positive ANAs in under 65 year olds are positive for no reason.
But if you're in the 28% of people with a positive ANA and have a rheumatological condition you may have…..
Polymyositis & dermatomyositis
Idiopathic thrombocytopenic purpura
Autoimmune hemolytic anemia
Type I diabetes mellitus
Mixed connective tissue disorder
It also depends on what pattern your ANA is as it can point towards a specific condition, for example…
Systemic Lupus Erythematosus
Systemic Lupus Erythematosus (Very specific)
Most common, least specific
Systemic Lupus Erythematosus
Mixed Connective Tissue Disease
But no blood test on its own is enough evidence for anything. You need to have symptoms and meet the other criteria.
It's a good thing you're seeing a rheumatologist. They'll be able to work out what's going on and whether your ANA is positive because you have an autoimmune disease.
Positive ANA indicates a autoimmune disease. A rheumotologist should be helpful. We can not really diagnose you, but a rheumotologist should be able to give you a diagnosis.
Got a better answer? Share it below!
Incoming search terms:
- ana 1:160 speckled
- positive ana icd 9
- ana titer 1 640 speckled
- Ana 640
- ana positive speckled 1 40
- ana 320
- ana positive speckled 1 160
- does type 1 diabetes have a positive ana
- do all type 1 diabetics have a higher ana titer
- diabetes and positive ana